Testosterone: Action, Deficiency, SubstitutionEberhard Nieschlag, Hermann M. Behre, Susan Nieschlag Now in its fourth edition Testosterone: Action, Deficiency, Substitution provides the most up-to-date and comprehensive source of information on testosterone and its role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behavior, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and the prostate. The therapeutic uses of testosterone preparations are carefully evaluated as well as its abuse and detection in competitive sport. This new edition also devotes sections to exploring the effects of testosterone on female physiology and sexual function, and the experimental use of testosterone in male hormonal contraception. Testosterone: Action, Deficiency, Substitution has been written and edited by world experts in the fields of clinical andrology and endocrinology and provides a unique and invaluable guide for andrologists, endocrinologists, urologists, internists and those working in reproductive medicine. |
Contents
| 1 | |
| 15 | |
Pathophysiology of the androgen receptor | 33 |
Methodology for measuring testosterone dihydrotestosterone and sex hormonebinding globulin in a clinical setting | 60 |
The behavioral correlates of testosterone | 87 |
The role of testosterone in spermatogenesis | 123 |
Androgens and hair a biological paradox with clinical consequences | 154 |
Testosterone and bone | 177 |
Testosterone preparations for clinical use in males | 309 |
Androgens in male senescence | 336 |
Androgen therapy in nongonadal disease | 372 |
Review of guidelines on diagnosis and treatment of testosterone deficiency | 408 |
Pathophysiology of estrogen action in men | 421 |
Dehydroepiandrosterone and androstenedione | 437 |
The stateoftheart in the development of selective androgen receptor modulators | 459 |
The essential role of testosterone in hormonal male contraception | 470 |
Androgen effects on the skeletal muscle | 191 |
Testosterone and cardiovascular disease | 207 |
Testosterone obesity diabetes and the metabolic syndrome | 235 |
Testosterone and erection | 251 |
Testosterone and the prostate | 268 |
Clinical use of testosterone in hypogonadism and other conditions | 292 |
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Common terms and phrases
activity anabolic anabolic steroids androgen action androgen receptor androgen therapy androgenetic alopecia androstenedione aromatase associated azoospermia Behre benefit Bhasin bioavailable Biol bone CAG repeat cardiovascular Clin Endocrinol Metab clinical decreased deficiency dehydroepiandrosterone DHEA dihydrotestosterone disease dose effects of testosterone efficacy elderly Endocr Endocrinology endogenous erectile estradiol estrogen factors first free testosterone GnRH gonadotropin Handelsman healthy hormone human hypogonadal improve increase influence injection insulin Leydig cells low testosterone male contraception mass metabolic syndrome muscle nandrolone Nieschlag nmol/l normal oral osteoporosis patients placebo placebo-controlled plasma polymorphism postmenopausal women prostate cancer protein puberty randomized reproductive risk Rochira role SARMs Sertoli cells serum levels serum testosterone levels sex steroid sexual function SHBG significant significantly specific sperm spermatogenesis suppression terone testicular testis testos testoster testosterone enanthate testosterone replacement testosterone therapy testosterone treatment testosterone undecanoate tion tissue tosterone total testosterone trial Wang